SCHEMBL27486563

SCHEMBL27486563

CCCCC(CCCC)C(=O)OCCCO

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.50
CA1 P00915 4/20 0.50
HDAC3 O15379 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
HDAC9 Q9UKV0 1/20 0.46
HDAC5 Q9UQL6 1/20 0.46
MAPK1 P28482 1/20 0.45
ALDH1A1 P00352 1/20 0.43
ACHE P22303 6/20 0.43
ATM Q13315 1/20 0.41
NAAA Q02083 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9327517 0.92 CA2 (0.61) CA2CA1HDAC3HDAC4HDAC1
SCHEMBL2151342 0.92 HDAC1 (0.53) CA2CA1HDAC3HDAC4HDAC1
SCHEMBL4314783 0.91 NAAA (0.48) CA2CA1HDAC3HDAC4HDAC1
SCHEMBL32681988 0.91 CA2 (0.46) CA2CA1HDAC3HDAC4HDAC1
SCHEMBL12157091 0.90 HDAC1 (0.49) CA2CA1HDAC3HDAC4HDAC1
SCHEMBL1428342 0.90 CA2 (0.52) CA2CA1HDAC3HDAC4HDAC1
SCHEMBL28878379 0.90 CA2 (0.52) CA2CA1HDAC3HDAC4HDAC1
SCHEMBL1727807 0.90 CA2 (0.55) CA2CA1HDAC3HDAC4HDAC1
SCHEMBL62982 0.90 CA2 (0.55) CA2CA1HDAC3HDAC4HDAC1
SCHEMBL17363998 0.89 ACHE (0.50) CA2CA1ALDH1A1ACHENAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117357481-A Preparation process of oral taste-masking pharmaceutical composition 杭州同惠医药科技有限公司 2024-01-09 CN claimed
CN-113056262-B Prolyl hydroxylase inhibitor pharmaceutical composition and preparation method thereof 江苏恒瑞医药股份有限公司 2022-11-18 CN claimed
CN-112641718-A Taste-masking compound based on porous carrier and preparation method and application thereof 山东大学 2021-04-13 CN claimed
CN-105106127-A Montmorillonite pellet dry suspension and preparation method thereof HENAN LIFE PHARMACEUTICAL CO LTD 2015-12-02 CN claimed
CN-1526449-A Method of eliminating and inhibiting bitter of medicine 上海现代浦东药厂有限公司 2004-09-08 CN claimed
CN-117357481-A Preparation process of oral taste-masking pharmaceutical composition 杭州同惠医药科技有限公司 2024-01-09 CN disclosed
CN-114246837-A Epalrestat micro-tablet and preparation method thereof 山东达因海洋生物制药股份有限公司 2022-03-29 CN disclosed
CN-113056262-A Prolyl hydroxylase inhibitor pharmaceutical composition and preparation method thereof 江苏恒瑞医药股份有限公司 2021-06-29 CN disclosed
CN-105106127-A Montmorillonite pellet dry suspension and preparation method thereof HENAN LIFE PHARMACEUTICAL CO LTD 2015-12-02 CN disclosed
CN-1526449-A Method of eliminating and inhibiting bitter of medicine 上海现代浦东药厂有限公司 2004-09-08 CN disclosed
CN-1260183-A Cactus granule preparation and its preparation method ZHEJIANG PROVINCIAL PEOPLE S H (CN) 2000-07-19 CN disclosed
CN-1104093-A Method for preparation of ferrous sulfate compound release-controlling preparation GUANGZHOU XINGHUA PHARMACEUTIC (CN) 1995-06-28 CN disclosed