Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 2/20 | 0.43 |
| ▸ | CCND1 | P24385 | 2/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL594405 | 0.82 | AHR (0.50) | AHRKEAP1CDK4CCND1PDPK1 | |
| SCHEMBL24034931 | 0.81 | AHR (0.46) | AHRKEAP1PDPK1NR3C1REN | |
| SCHEMBL6089266 | 0.81 | AHR (0.46) | AHRKEAP1PDPK1NR3C1ABL1 | |
| SCHEMBL31492457 | 0.80 | AHR (0.60) | AHRKEAP1PDPK1NR3C1REN | |
| SCHEMBL5662384 | 0.78 | KEAP1 (0.46) | AHRKEAP1PDPK1NR3C1MAPT | |
| SCHEMBL6251056 | 0.78 | AHR (0.46) | AHRKEAP1PDPK1NR3C1REN | |
| SCHEMBL18000230 | 0.78 | PIK3CD (0.54) | AHRKEAP1PDPK1NR3C1ALDH1A1 | |
| SCHEMBL7084949 | 0.77 | MAPT (0.46) | AHRKEAP1PDPK1NR3C1ALDH1A1 | |
| SCHEMBL5659443 | 0.77 | REN (0.49) | AHRKEAP1PDPK1NR3C1HPGD | |
| SCHEMBL7091090 | 0.77 | AHR (0.42) | AHRKEAP1PDPK1NR3C1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105120863-A | Alkylamine peganine derivatives for promoting bone growth | OSTEOQC INC | 2015-12-02 | — | — | CN | claimed |
| CN-101631787-A | Tricyclic isoquinoline derivatives for the treatment of obesity | BIOVITRUM AB PUBL | 2010-01-20 | — | — | CN | claimed |
| CN-105120863-A | Alkylamine peganine derivatives for promoting bone growth | OSTEOQC INC | 2015-12-02 | — | — | CN | disclosed |
| CN-101631787-A | Tricyclic isoquinoline derivatives for the treatment of obesity | BIOVITRUM AB PUBL | 2010-01-20 | — | — | CN | disclosed |
| CN-1937994-A | Keratin dyeing compounds, keratin dyeing compositions containing them and their use | PROCTER & GAMBLE (US) | 2007-03-28 | — | — | CN | disclosed |
| CN-1937995-A | Keratin dyeing compositions comprising bicyclic 5-6 heteroaromatic dyeing compounds containing a ring-connected nitrogen atom | PROCTER & GAMBLE (US) | 2007-03-28 | — | — | CN | disclosed |
| CN-1264498-C | Primary intermediates for oxidative dyeing of hair | PROCTER & GAMBLE (US) | 2006-07-19 | — | — | CN | disclosed |
| CN-1239467-C | Primary intermediates for oxidative dyeing of hair | P & G CLAIROL INC (US) | 2006-02-01 | — | — | CN | disclosed |
| CN-1229102-C | Novel couplers for oxidative hair dyeing | P & G CLAIROL INC (US) | 2005-11-30 | — | — | CN | disclosed |
| CN-1229100-C | Primary intermediates for oxidative dyeing of hair | P & G CLAIROL INC (US) | 2005-11-30 | — | — | CN | disclosed |
| CN-1224374-C | Novel couplers for oxidative hair dyeing | P & G CLAIROL INC (US) | 2005-10-26 | — | — | CN | disclosed |
| CN-1486297-A | Primary intermediates for oxidative dyeing of hair | P&G | 2004-03-31 | — | — | CN | disclosed |
| CN-1486172-A | Primary intermediates for oxidative dyeing of hair | P&G | 2004-03-31 | — | — | CN | disclosed |
| CN-1486170-A | Novel couplers for use in oxidative hair dyeing | P&G | 2004-03-31 | — | — | CN | disclosed |
| CN-1477947-A | Primary intermediates for oxidative dyeing of hair | P&G | 2004-02-25 | — | — | CN | disclosed |
| CN-1477948-A | Novel couplers for oxidative hair dyeing | P&G克莱罗尔公司 | 2004-02-25 | — | — | CN | disclosed |
| CN-1474681-A | Novel couplers for oxidative hair dyeing | P&G克莱罗尔公司 | 2004-02-11 | — | — | CN | disclosed |
| CN-1474680-A | Novel couplers for oxidative hair dyeing | P&G克莱罗尔公司 | 2004-02-11 | — | — | CN | disclosed |
| CN-1474679-A | Novel couplers for oxidative hair dyeing | P&G | 2004-02-11 | — | — | CN | disclosed |
| CN-1449276-A | Primary intermediates for oxidative dyeing of hair | P & G CLAIROL INC (US) | 2003-10-15 | — | — | CN | disclosed |