Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | REN | P00797 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24034931 | 0.81 | AHR (0.46) | AHRBCHERENNR3C1KEAP1 | |
| SCHEMBL594405 | 0.78 | AHR (0.50) | MAPTAHRRENNR3C1KEAP1 | |
| SCHEMBL27487511 | 0.77 | AHR (0.46) | MAPTNPSR1AHRBCHEREN | |
| SCHEMBL6089266 | 0.77 | AHR (0.46) | AHRBCHERENNR3C1KEAP1 | |
| SCHEMBL5659443 | 0.77 | REN (0.49) | RAB9AAHRBCHERENNR3C1 | |
| SCHEMBL7091090 | 0.77 | AHR (0.42) | RAB9AAHRBCHERENNR3C1 | |
| SCHEMBL31492457 | 0.75 | AHR (0.60) | AHRBCHERENNR3C1KEAP1 | |
| SCHEMBL5662384 | 0.74 | KEAP1 (0.46) | MAPTAHRBCHERENNR3C1 | |
| SCHEMBL18000230 | 0.74 | PIK3CD (0.54) | MAPTKDM4ERAB9AAHRREN | |
| SCHEMBL6251056 | 0.74 | AHR (0.46) | AHRBCHERENNR3C1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203959-A1 | Novel modulators of potassium channels | 4SC AG (DE) | 2003-10-30 | — | — | US | disclosed |
| WO-2003074047-A1 | INDOLE DERIVATIVES AS MODULATORS OF POTASSIUM CHANNELS | 4SC AG (DE) | 2003-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203959-A1 | Novel modulators of potassium channels | HCN3, KCNN3, KCNN1 | MAPT 4860/4885KDM4E 2893/4885RAB9A 3394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.