Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 18/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 9/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27472001 | 0.88 | NPBWR1 (0.53) | NPBWR1NPSR1ALDH1A1MCHR1PTGS1 | |
| SCHEMBL27489269 | 0.87 | NPBWR1 (0.52) | NPBWR1NPSR1ALDH1A1MCHR1PTGS1 | |
| SCHEMBL27522830 | 0.84 | PTGS2 (0.46) | NPBWR1NPSR1ALDH1A1MCHR1PTGS1 | |
| SCHEMBL27488950 | 0.84 | NPBWR1 (0.40) | NPBWR1NPSR1ALDH1A1MCHR1PTGS1 | |
| SCHEMBL27470076 | 0.83 | PTGS2 (0.71) | NPBWR1NPSR1MCHR1PTGS1PTGS2 | |
| SCHEMBL27487167 | 0.83 | NPBWR1 (0.40) | NPBWR1NPSR1ALDH1A1MCHR1PTGS1 | |
| SCHEMBL27547550 | 0.83 | NPBWR1 (0.40) | NPBWR1NPSR1ALDH1A1MCHR1PTGS1 | |
| SCHEMBL27486814 | 0.81 | NPBWR1 (0.42) | NPBWR1NPSR1ALDH1A1MCHR1 | |
| SCHEMBL27487895 | 0.81 | MEN1 (0.42) | NPBWR1NPSR1ALDH1A1MCHR1 | |
| SCHEMBL27488957 | 0.81 | SMN1; SMN2 (0.40) | NPBWR1NPSR1ALDH1A1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |
| CN-1277605-A | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LAB (US) | 2000-12-20 | — | — | CN | disclosed |