Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 18/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 13/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27471540 | 0.92 | NPBWR1 (0.47) | NPBWR1MCHR1PTGS1PTGS2NPSR1 | |
| SCHEMBL27489269 | 0.90 | NPBWR1 (0.52) | NPBWR1MCHR1PTGS1PTGS2NPSR1 | |
| SCHEMBL27487523 | 0.88 | NPBWR1 (0.53) | NPBWR1MCHR1PTGS1PTGS2NPSR1 | |
| SCHEMBL27549351 | 0.85 | RAB9A (0.44) | NPBWR1MCHR1PTGS1PTGS2NPSR1 | |
| SCHEMBL27549880 | 0.85 | NPBWR1 (0.40) | NPBWR1MCHR1PTGS1PTGS2NPSR1 | |
| SCHEMBL27472008 | 0.83 | RAB9A (0.42) | NPBWR1MCHR1NPSR1ALDH1A1CYP1A2 | |
| SCHEMBL4191858 | 0.83 | PTGS2 (0.64) | NPBWR1MCHR1PTGS1PTGS2NPSR1 | |
| SCHEMBL27555439 | 0.82 | NPBWR1 (0.45) | NPBWR1MCHR1SMN1; SMN2 | |
| SCHEMBL27522818 | 0.81 | NPC1 (0.47) | NPBWR1MCHR1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL27471548 | 0.81 | SMN1; SMN2 (0.52) | NPBWR1MCHR1NPSR1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |