Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1578636 | 0.85 | MEN1 (0.43) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL1578367 | 0.83 | MEN1 (0.42) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL6631895 | 0.80 | MEN1 (0.45) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL27522882 | 0.80 | KDM4E (0.52) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL283096 | 0.79 | ALDH1A1 (0.50) | KMT2AALDH1A1KDM4E | |
| SCHEMBL15810094 | 0.76 | MAPT (0.45) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL27504682 | 0.76 | NCF1 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6176426 | 0.76 | KDM4E (0.43) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL19441301 | 0.75 | MEN1 (0.46) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL5669102 | 0.74 | TSHR (0.54) | MEN1KMT2AALDH1A1HTTNSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1213040-C | Serine protease inhibitors | LILLY CO ELI (US) | 2005-08-03 | — | — | CN | disclosed |
| CN-1438999-A | Serine protease inhibitors | LILLY CO ELI (US) | 2003-08-27 | — | — | CN | disclosed |