Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 6/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27489310 | 0.83 | KDM4E (0.40) | FLT3PYGLIDO1LOXL2TDO2 | |
| SCHEMBL27782152 | 0.82 | PYGL (0.35) | FLT3PYGLCYP19A1IDO1FFAR1 | |
| SCHEMBL27487578 | 0.81 | LOXL2 (0.47) | LOXL2HRH4 | |
| SCHEMBL27570412 | 0.75 | ALOX15 (0.46) | FLT3LOXL2HRH4SMN1; SMN2 | |
| SCHEMBL27650372 | 0.74 | CYP19A1 (0.39) | FLT3CYP19A1IDO1LOXL2HRH4 | |
| SCHEMBL16440998 | 0.72 | CYP19A1 (0.47) | FLT3CYP19A1IDO1LOXL2HRH4 | |
| SCHEMBL865591 | 0.71 | CYP19A1 (0.50) | FLT3CYP19A1IDO1LOXL2HRH4 | |
| SCHEMBL22529411 | 0.71 | CYP19A1 (0.46) | CYP19A1IDO1LOXL2SMN1; SMN2 | |
| SCHEMBL454982 | 0.70 | PYGL (0.43) | FLT3PYGLCYP19A1IDO1HRH4 | |
| SCHEMBL454981 | 0.70 | PYGL (0.43) | FLT3PYGLCYP19A1IDO1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101743232-B | Compounds and methods for modulating fxr | LILLY CO ELI | 2013-03-06 | — | — | CN | disclosed |
| CN-101421252-B | 2, 6-substituted-4-monosubstituted aminopyrimidines as prostaglandin D2 receptor antagonists | SANOFI AVENTIS | 2011-10-12 | — | — | CN | disclosed |
| CN-101743232-A | Regulate the Compounds and methods for of FXR | LILLY CO ELI | 2010-06-16 | — | — | CN | disclosed |
| CN-101421252-A | 2, 6-substituted-4-monosubstituted aminopyrimidines as prostaglandin D2 receptor antagonists | SANOFI AVENTIS (FR) | 2009-04-29 | — | — | CN | disclosed |