Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | S100B | P04271 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9480117 | 0.93 | S100B (0.44) | ESR1ESR2MEN1KMT2AS100B | |
| SCHEMBL27438595 | 0.79 | ALDH1A1 (0.43) | MMP3BCL2L1CA12CA1CA2 | |
| Phenol SCHEMBL27827991 | 0.77 | TDP1 (0.50) | ESR1ESR2MMP3BCL2L1MEN1 | |
| SCHEMBL15608468 | 0.77 | TDP1 (0.50) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL9245112 | 0.73 | ESR1 (0.58) | ESR1ESR2MMP3BCL2L1ABL1 | |
| SCHEMBL21242225 | 0.72 | NPC1 (0.67) | ESR1ESR2MMP3BCL2L1ABL1 | |
| SCHEMBL12534430 | 0.72 | NPC1 (0.67) | ESR1ESR2MMP3BCL2L1ABL1 | |
| Hydroquinone SCHEMBL5712110 | 0.71 | ESR1 (1.00) | ESR1ESR2MMP3BCL2L1ABL1 | |
| SCHEMBL6292004 | 0.71 | ESR1 (1.00) | ESR1ESR2MMP3BCL2L1ABL1 | |
| SCHEMBL9090705 | 0.71 | ESR1 (1.00) | ESR1ESR2MMP3BCL2L1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1178906-C | N-hydroxyformamide derivatives as inhibitors of matrix metalloproteinases | ���Ͽع�����˾ | 2004-12-08 | — | — | CN | disclosed |
| CN-1261876-A | N-hydroxyformamide derivatives as inhibitors of matrix metalloproteinases | ABBOTT LAB (US) | 2000-08-02 | — | — | CN | disclosed |