Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.30 |
| ▸ | MEN1 | O00255 | 3/20 | 0.30 |
| ▸ | RAB9A | P51151 | 3/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18528954 | 0.82 | TP53 (0.46) | NPC1TP53MAPTHSD17B10TLR9 | |
| SCHEMBL27407913 | 0.81 | NPC1 (0.34) | NPC1TP53MAPTHSD17B10TLR9 | |
| SCHEMBL9195002 | 0.73 | HSD17B10 (0.39) | MAPTHSD17B10CHEK1NTRK2KMT2A | |
| SCHEMBL28283383 | 0.72 | TLR9 (0.49) | NPC1TP53MAPTHSD17B10TLR9 | |
| SCHEMBL630361 | 0.71 | KMT2A (0.36) | NPC1MAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL2160060 | 0.70 | HCAR2 (0.35) | TP53HSD17B10ALDH1A1MAPK1CHEK1 | |
| SCHEMBL31456656 | 0.68 | TP53 (0.44) | NPC1TP53MAPTHSD17B10TLR9 | |
| SCHEMBL21884143 | 0.67 | ALDH1A1 (0.34) | MAPTALDH1A1NPSR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL15963465 | 0.67 | GRM4 (0.41) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2159923 | 0.67 | MEN1 (0.33) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102120741-A | Production method of an optically active compound | MITSUBISHI TANABE PHARMA CORP | 2011-07-13 | — | — | CN | disclosed |
| CN-102050820-A | Preparation method of compound with optical activity | MITSUBISHI TANABE PHARMA CORP | 2011-05-11 | — | — | CN | disclosed |
| CN-101228142-A | Intermediate compounds for the synthesis of pharmaceutical preparations, and process for their preparation | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-07-23 | — | — | CN | disclosed |
| CN-1212694-A | Pyrimido [5,4-D] pyrimidines, medicaments containing these compounds, their use and process for their production | THOMAE GMBH DR K (DE) | 1999-03-31 | — | — | CN | disclosed |
| CN-1212696-A | Pyrimido [5, 4-d ] pyrimidines, medicaments containing these compounds, their use and processes for their preparation | THOMAE GMBH DR K (DE) | 1999-03-31 | — | — | CN | disclosed |