Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27453910 | 0.85 | TXNRD1 (0.44) | MAPTALDH1A1HTTTDP1KDM4E | |
| SCHEMBL27503692 | 0.84 | ALDH1A1 (0.40) | NQO2MAPTALDH1A1HTTLMNA | |
| SCHEMBL27480411 | 0.73 | POLB (0.45) | MAPTALDH1A1HTTLMNATDP1 | |
| SCHEMBL25219845 | 0.70 | NQO2 (0.55) | NQO2LCKMAPTALDH1A1HTT | |
| SCHEMBL5756956 | 0.66 | NQO2 (0.50) | NQO2LCKMAPTALDH1A1HTT | |
| SCHEMBL28322665 | 0.66 | GRIA1 (0.56) | MAPTALDH1A1HTTLMNATDP1 | |
| SCHEMBL27547765 | 0.66 | NQO2 (0.36) | NQO2MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL1361650 | 0.65 | NQO2 (0.49) | NQO2MAPTALDH1A1HTTTDP1 | |
| SCHEMBL8087024 | 0.65 | NQO2 (0.60) | NQO2MAPTALDH1A1HTTLMNA | |
| SCHEMBL27449490 | 0.65 | NQO2 (0.31) | NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1193968-A | 2,3-dioxo-1,2,3,4-tetrahydro-quinoyxalinyl derivatives | NOVARTIS AG (CH) | 1998-09-23 | — | — | CN | disclosed |