Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | ENO1 | P06733 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27647485 | 0.93 | RIPK1 (0.33) | RIPK1ENO1 | |
| SCHEMBL27637686 | 0.89 | RIPK1 (0.32) | ELANERIPK1 | |
| SCHEMBL27597099 | 0.82 | — | — | |
| SCHEMBL28788331 | 0.82 | — | — | |
| SCHEMBL2564447 | 0.81 | USP2 (0.33) | KCNQ2ELANE | |
| SCHEMBL4307041 | 0.80 | — | — | |
| SCHEMBL28873270 | 0.79 | MMP2 (0.31) | — | |
| SCHEMBL22720789 | 0.79 | POLB (0.33) | POLBGAANPSR1ELANE | |
| SCHEMBL27855997 | 0.79 | CA1 (0.36) | ENO1KMT2A | |
| SCHEMBL8431323 | 0.79 | HPGD (0.33) | ELANERIPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520413-A | Big ring broad-spectrum antibiotic | RQX PHARMACEUTICALS INC | 2019-11-29 | — | — | CN | disclosed |
| CN-105916845-B | N- heteroaryl compound and composition for inhibiting the active N- azaspiro cycloalkanes of SHP2 to replace | 诺华股份有限公司 | 2019-11-12 | — | — | CN | disclosed |
| CN-106946867-B | FXR receptor modulators and its preparation method and application | 广州市恒诺康医药科技有限公司 | 2019-11-12 | — | — | CN | disclosed |
| CN-104974161-B | The analog of 4H- pyrazolo [1,5- α] benzimidazole compound as PARP inhibitor | Hubei company limited of Bio-pharmaceutical Industry Institute for Research and Technology (CN) | 2019-11-01 | — | — | CN | disclosed |
| CN-110392688-A | For inhibiting the compound of ROR- γ-T | 伊莱利利公司 | 2019-10-29 | — | — | CN | disclosed |
| CN-110386932-A | For the dual ATM and DNA-PK inhibitor in antitumor therapy | 艾科思莱德制药公司 | 2019-10-29 | — | — | CN | disclosed |
| CN-110392678-A | For the IDO and TDO Compounds and methods for adjusted and its indication | 普莱希科公司 | 2019-10-29 | — | — | CN | disclosed |
| CN-106061963-B | Heterocyclic modulators of lipid synthesis and combinations thereof | 3-V生物科学股份有限公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-110337440-A | It can be used for inhibiting the compound of ROR- γ-t | 伊莱利利公司 | 2019-10-15 | — | — | CN | disclosed |
| CN-106459083-B | Amide derivatives with the active 1- oxa- -4,9- diaza spiro hendecane compound of the anti-pain of multiplex mode | 埃斯蒂文制药股份有限公司 | 2019-10-01 | — | — | CN | disclosed |
| CN-1468237-A | Substituted pyrazoles | 奥索-麦克尼尔药品公司 | 2004-01-14 | — | — | CN | disclosed |
| CN-1468239-A | Substituted pyrazoles | ����-������ҩƷ��˾ | 2004-01-14 | — | — | CN | disclosed |
| CN-1468238-A | Substituted pyrazoles | ����-������ҩƷ��˾ | 2004-01-14 | — | — | CN | disclosed |
| CN-1426393-A | Novel compounds | ASTRAZENECA AB (SE) | 2003-06-25 | — | — | CN | disclosed |
| CN-1425002-A | Pyrrolidine and piperidine derivatives and their use for treatment of neurodegenerative disorders | HOFFMANN LA ROCHE (CH) | 2003-06-18 | — | — | CN | disclosed |
| CN-1351497-A | Aminopyrimidines as sorbitol dehydrogenase inhibitors | PFIZER PROD INC (US) | 2002-05-29 | — | — | CN | disclosed |
| CN-1344256-A | (Hetero) aryl-bicyclic heteroaryl derivatives, their prepn. and their use as protease inhibitors | AXYS PHARM INC (US) | 2002-04-10 | — | — | CN | disclosed |
| CN-1281433-A | Hydroxamic acid derivatives as matrix metalloproteinase (MMP) inhibitors | PFIZER LTD (US) | 2001-01-24 | — | — | CN | disclosed |
| CN-1211991-A | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 1999-03-24 | — | — | CN | disclosed |
| CN-1202152-A | Novel 4- (oxoxyphenyl) -3-oxopiperidines for the treatment of cardiac and renal insufficiency | HOFFMANN LA ROCHE (CH) | 1998-12-16 | — | — | CN | disclosed |