Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27613210 | 0.89 | RIPK1 (0.36) | RIPK1 | |
| SCHEMBL27488043 | 0.89 | KCNQ2 (0.31) | RIPK1ELANE | |
| SCHEMBL27861105 | 0.88 | CNR1 (0.34) | RIPK1ELANE | |
| SCHEMBL22720789 | 0.84 | POLB (0.33) | ELANE | |
| SCHEMBL27647485 | 0.82 | RIPK1 (0.33) | RIPK1 | |
| SCHEMBL5036518 | 0.82 | ESR2 (0.33) | ELANE | |
| SCHEMBL27653281 | 0.80 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL27720657 | 0.79 | GLA (0.30) | — | |
| SCHEMBL27597099 | 0.76 | — | — | |
| SCHEMBL27932516 | 0.75 | PIK3CD (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110475777-A | For treating and preventing new pyrido [2,3-b] benzazolyl compounds of bacterium infection | HOFFMANN LA ROCHE | 2019-11-19 | — | — | CN | disclosed |
| CN-110072864-A | TDO2 INHIBITORS | 基因泰克公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-109996790-A | Piperazine carbamate and its preparation and application | 阿比德治疗公司 | 2019-07-09 | — | — | CN | disclosed |
| CN-109790112-A | Cyanopyrrolidine derivatives having activity as USP30 inhibitors | 特殊治疗有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-109790157-A | New antimicrobial compound | 方济各安吉利克化学联合股份有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-105705501-B | ROR gamma modulators | 百时美施贵宝公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-109415366-A | Novel [1,2,3] triazol [4,5-d] pyrimidine derivatives | 豪夫迈·罗氏有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-109415343-A | For treating substituted 2,4- diamino-quinoline of proliferative diseases | 基因科学医药公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-109415373-A | New antimicrobial compound | 方济各安吉利克化学联合股份有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-109153648-A | Benzazepine diformamide compound with teritary amide functional group | 豪夫迈·罗氏有限公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-101874020-A | Piperidine derivatives as agonists of muscarinic receptors | ASTRAZENECA AB | 2010-10-27 | — | — | CN | disclosed |
| CN-100562319-C | 2-cyanopyrrole and pyrimidine and its pharmaceutical use | NOVARTIS AG (CH) | 2009-11-25 | — | — | CN | disclosed |
| CN-101501024-A | Muscarinic receptor agonists that are effective in the treatment of pain, alzheimer's disease and schizophrenia | ASTRAZENECA AB (SE) | 2009-08-05 | — | — | CN | disclosed |
| CN-101479266-A | Spiro-fused piperidines as modulators of muscarinic receptors | VERTEX PHARMA (US) | 2009-07-08 | — | — | CN | disclosed |
| CN-101421256-A | Thiadiazolidinone inhibitors of ptpase | NOVARTIS AG (CH) | 2009-04-29 | — | — | CN | disclosed |
| CN-101410400-A | Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes | MERCK & CO INC (US) | 2009-04-15 | — | — | CN | disclosed |
| CN-101001842-A | Amido compounds and their use as pharmaceuticals | INCYTE CORP (US) | 2007-07-18 | — | — | CN | disclosed |
| CN-1886392-A | Novel benzofuran derivatives, which can be used in prophylaxis or treatment of 5-ht6 receptor-related disorder | BIOVITRUM AKTIEBOLAG (SE) | 2006-12-27 | — | — | CN | disclosed |
| CN-1882590-A | Fused heterocyclic compounds as serotonin receptor modulators | JOHNSON & JOHNSON (BE) | 2006-12-20 | — | — | CN | disclosed |
| CN-1756553-A | 2-cyanopyrrolopyrimidines and pharmaceutical uses thereof | NOVARTIS AG (CH) | 2006-04-05 | — | — | CN | disclosed |