Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL27416790 | 0.84 | GLRA1 (0.53) | GLRA1SLC6A9OR51E2LMNACYP1A2 | |
| Carbamic Acid SCHEMBL27422028 | 0.80 | ACHE (0.44) | — | |
| SCHEMBL28173717 | 0.80 | KDM4E (0.38) | KDM4EALDH1A1LMNATP53CYP1A2 | |
| Carbamic Acid SCHEMBL28313671 | 0.78 | ACHE (0.41) | — | |
| SCHEMBL28866705 | 0.74 | CRBN (0.38) | LMNACYP1A2CYP3A4THPOBLM | |
| Hydroxyamine SCHEMBL5061248 | 0.73 | — | — | |
| SCHEMBL27942910 | 0.73 | — | — | |
| Aminomethylamide SCHEMBL1354065 | 0.72 | OR51E2 (0.54) | GLRA1SLC6A9OR51E2KDM4EGMNN | |
| Aminomethylamide SCHEMBL8299 | 0.72 | — | — | |
| Succinic Acid SCHEMBL2578311 | 0.70 | LMNA (0.50) | OR51E2KDM4ELMNAPOLBPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170283552-A1 | METHODS FOR PREPARING POLYMERIC REAGENTS AND COMPOSITIONS OF POLYMERIC REAGENTS | NEKTAR THERAPEUTICS | 2017-10-05 | — | — | US | disclosed |
| CN-1200727-C | Pharmaceutical compositions based on alpha-cyclodextrins for the oral administration of LH-RH analogues | THERAMEX (MC) | 2005-05-11 | — | — | CN | disclosed |
| CN-1324241-A | Pharmaceutical compositions based on alpha-cyclodextrin for the oral administration of LH-RH analogues | THERAMEX (MC) | 2001-11-28 | — | — | CN | disclosed |