Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | CDK9 | P50750 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3461792 | 0.86 | SMN1; SMN2 (0.59) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL775002 | 0.85 | NAMPT (0.56) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL27846204 | 0.85 | POLB (0.61) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL3460916 | 0.82 | KMT2A (0.55) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL15284035 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| Alcohol SCHEMBL4315662 | 0.79 | NAMPT (0.51) | SMN1; SMN2NPC1RAB9ACTSKLMNA | |
| SCHEMBL9479696 | 0.79 | MAPT (0.58) | SMN1; SMN2RAB9AKMT2AMEN1LMNA | |
| SCHEMBL27942342 | 0.79 | PDK1 (0.51) | SMN1; SMN2NPC1LMNAPOLBNAPRT | |
| SCHEMBL13785635 | 0.79 | CTSK (0.41) | NPC1RAB9AKMT2AMEN1CTSK | |
| SCHEMBL31617997 | 0.79 | EPHX1 (0.58) | SMN1; SMN2EPHX1KMT2AMEN1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161331-C | Hydrazine derivative | - | 2004-08-11 | — | — | CN | disclosed |
| CN-1265096-A | Hydrazine derivatives | HOFFMANN LA ROCHE (CH) | 2000-08-30 | — | — | CN | disclosed |