Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27487791 | 0.85 | ALOX5 (0.54) | HPGDALOX5HDAC3 | |
| SCHEMBL27488152 | 0.85 | LTB4R2 (0.46) | HPGDLTB4R2HTTLMNASMN1; SMN2 | |
| SCHEMBL1678232 | 0.78 | HDAC3 (0.47) | HPGDLTB4R2HTTLMNASMN1; SMN2 | |
| SCHEMBL27488515 | 0.77 | ALOX5 (0.55) | ALOX5 | |
| SCHEMBL10568746 | 0.77 | SMN1; SMN2 (0.50) | HPGDHTTLMNASMN1; SMN2TSHR | |
| SCHEMBL27488855 | 0.76 | CYP1A2 (0.46) | HPGDSMN1; SMN2TSHRCYP1A2CYP3A4 | |
| SCHEMBL7550214 | 0.76 | HDAC3 (0.44) | HPGDLTB4R2HTTLMNASMN1; SMN2 | |
| SCHEMBL11485292 | 0.74 | NPY5R (0.42) | LTB4R2LMNASMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL1677783 | 0.73 | CA12 (0.55) | LMNAALOX5CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27306760 | 0.73 | ALDH1A1 (0.54) | LMNAHDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161331-C | Hydrazine derivative | - | 2004-08-11 | — | — | CN | disclosed |
| CN-1265096-A | Hydrazine derivatives | HOFFMANN LA ROCHE (CH) | 2000-08-30 | — | — | CN | disclosed |