Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27488153 | 0.85 | HPGD (0.41) | LTB4R2HPGDHDAC3HDAC1HDAC2 | |
| SCHEMBL27339023 | 0.84 | LTB4R2 (0.52) | LTB4R2TSHRLMNAHSD17B10 | |
| SCHEMBL27469992 | 0.82 | CHRNB2 (0.49) | LTB4R2LMNAPKM | |
| SCHEMBL27487794 | 0.77 | ALDH1A1 (0.50) | HDAC3HDAC1HDAC2HTTALDH1A1 | |
| SCHEMBL7550214 | 0.75 | HDAC3 (0.44) | LTB4R2HPGDHDAC3HDAC1HDAC2 | |
| SCHEMBL11090009 | 0.75 | HPGD (0.48) | HPGDHDAC3HDAC1HDAC2HTT | |
| SCHEMBL27549223 | 0.75 | TRPM8 (0.44) | HPGDHTTTSHRALDH1A1NR1H2 | |
| SCHEMBL27475732 | 0.74 | PTGDR2 (0.50) | HDAC3HDAC1HDAC2SMN1; SMN2LMNA | |
| SCHEMBL11172546 | 0.72 | RAB9A (0.56) | HTTUSP2TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL4004765 | 0.71 | NAAA (0.47) | HPGDHDAC3HDAC1HDAC2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161331-C | Hydrazine derivative | - | 2004-08-11 | — | — | CN | disclosed |
| CN-1265096-A | Hydrazine derivatives | HOFFMANN LA ROCHE (CH) | 2000-08-30 | — | — | CN | disclosed |