Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | PTPRC | P08575 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.40 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791706 | 0.86 | ALDH1A1 (0.46) | ALDH1A1HSD17B10TDP1MEN1KMT2A | |
| SCHEMBL6291104 | 0.84 | ALDH1A1 (0.43) | ALDH1A1HSD17B10TDP1MEN1KMT2A | |
| SCHEMBL197834 | 0.83 | ACHE (0.47) | ALDH1A1MEN1KMT2ANPSR1PTPRC | |
| SCHEMBL29547174 | 0.83 | ACHE (0.47) | ALDH1A1MEN1KMT2ANPSR1PTPRC | |
| SCHEMBL14119978 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TDP1NPSR1PTPRC | |
| SCHEMBL30389980 | 0.80 | PTPRC (0.48) | ALDH1A1MEN1KMT2ANPSR1PTPRC | |
| Hydrogen Sulfide SCHEMBL10700223 | 0.80 | ACHE (0.45) | ALDH1A1MEN1KMT2ANPSR1PTPRC | |
| SCHEMBL5706297 | 0.80 | PTPRC (0.48) | ALDH1A1MEN1KMT2ANPSR1PTPRC | |
| SCHEMBL7333015 | 0.80 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TDP1MEN1KMT2A | |
| SCHEMBL14956305 | 0.78 | GAA (0.43) | MEN1KMT2ANPSR1PTPRCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1169730-A | Aromatic heterocyclic derivatives as enzyme inhibitors | CORVAS INT INC (US) | 1998-01-07 | — | — | CN | disclosed |