Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27487891 | 0.91 | RAB9A (0.40) | RAB9ANPC1ATMKMT2APKM | |
| SCHEMBL8519579 | 0.85 | PTGS2 (0.46) | RAB9ANPC1ATMKMT2APKM | |
| SCHEMBL27489266 | 0.84 | RAB9A (0.44) | RAB9ANPC1ATMKMT2APKM | |
| SCHEMBL4183881 | 0.84 | PTGS2 (0.47) | RAB9ANPC1ATMKMT2APKM | |
| SCHEMBL27522824 | 0.83 | RAB9A (0.42) | RAB9ANPC1ATMKMT2APKM | |
| SCHEMBL27471996 | 0.82 | RAB9A (0.42) | RAB9ANPC1ATMKMT2APKM | |
| SCHEMBL27549348 | 0.82 | RAB9A (0.42) | RAB9ANPC1ATMKMT2APKM | |
| SCHEMBL27486810 | 0.81 | RAB9A (0.42) | RAB9ANPC1ATMKMT2APKM | |
| SCHEMBL27488954 | 0.81 | NPBWR1 (0.40) | RAB9ANPC1ATMKMT2APKM | |
| SCHEMBL27486812 | 0.80 | RAB9A (0.49) | RAB9ANPC1ATMKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |