Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290049 | 0.79 | POLB (0.46) | CYP4F2CYP4A11CYP2C19CYP2C9AKT1 | |
| SCHEMBL13684398 | 0.77 | HTT (0.49) | P4HBALDH1A1GAAMAPTMEN1 | |
| SCHEMBL29080079 | 0.75 | TTR (0.37) | CYP4F2CYP4A11P4HBALDH1A1GAA | |
| SCHEMBL18838874 | 0.72 | NFE2L2 (0.59) | ALDH1A1POLBGAAMEN1HPGD | |
| SCHEMBL3362670 | 0.71 | SLC7A5 (0.55) | CYP4F2CYP4A11ALDH1A1GAAMAPT | |
| SCHEMBL27966375 | 0.71 | UNG (0.31) | ALDH1A1 | |
| SCHEMBL18334864 | 0.69 | PTGS2 (0.55) | CYP4F2CYP4A11CYP2C19ALDH1A1GAA | |
| SCHEMBL23523217 | 0.69 | ALDH1A1 (0.53) | CYSLTR2CYSLTR1CYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL7220813 | 0.68 | — | — | |
| SCHEMBL28041988 | 0.67 | TP53 (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1178913-C | Aromatic heterocycle compounds having HIV integrase inhibiting activities | ��Ұ����ҩ��ʽ���� | 2004-12-08 | — | — | CN | disclosed |