Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 8/20 | 0.56 |
| ▸ | MMP1 | P03956 | 8/20 | 0.56 |
| ▸ | MMP13 | P45452 | 7/20 | 0.56 |
| ▸ | MMP3 | P08254 | 4/20 | 0.56 |
| ▸ | MMP7 | P09237 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 4/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.52 |
| ▸ | MMP14 | P50281 | 1/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765009 | 0.91 | MMP1 (0.58) | MMP9MMP1MMP13MMP3MMP7 | |
| SCHEMBL6347543 | 0.88 | MMP1 (0.74) | MMP9MMP1MMP13MMP3MMP7 | |
| SCHEMBL6339516 | 0.88 | MMP1 (0.74) | MMP9MMP1MMP13MMP3MMP7 | |
| Hydrochloric Acid SCHEMBL6337126 | 0.87 | MMP1 (0.73) | MMP9MMP1MMP13MMP3MMP7 | |
| Hydrochloric Acid SCHEMBL7349934 | 0.83 | MMP1 (0.75) | MMP9MMP1MMP13MMP3MMP7 | |
| SCHEMBL7369631 | 0.81 | MMP1 (0.56) | MMP9MMP1MMP13MMP3MMP7 | |
| SCHEMBL7226993 | 0.80 | ITGB1 (0.50) | MMP9MMP1MMP13MMP3MMP7 | |
| SCHEMBL7226992 | 0.80 | ITGB1 (0.50) | MMP9MMP1MMP13MMP3MMP7 | |
| SCHEMBL27583610 | 0.80 | MMP1 (0.54) | MMP9MMP1MMP13MMP3MMP7 | |
| Hydrochloric Acid SCHEMBL7454639 | 0.79 | ITGB1 (0.49) | MMP9MMP1MMP13MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1207289-C | Metalloprotease inhibitors, pharmaceutical compositions containing them and their use as medicaments, process and intermediates for their preparation | AGOURON PHARMA (US) | 2005-06-22 | — | — | CN | disclosed |
| CN-1542002-A | Inhibitors of metalloproteinase, pharmaceutical compositions containing them, their pharmaceutical application and methods and intermediate compounds for their preparation | ������ҩ������˾ | 2004-11-03 | — | — | CN | disclosed |
| CN-1207734-A | Metalloprotease inhibitors, pharmaceutical compositions containing them and their use as medicaments, process and intermediates for their preparation | AGOURON PHARMA (US) | 1999-02-10 | — | — | CN | disclosed |