SCHEMBL27488691

SCHEMBL27488691

Oc1cccc(OOCc2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.50
DRD4 P21917 1/20 0.50
ADRA1D P25100 1/20 0.50
ADRA1A P35348 1/20 0.50
ADRA1B P35368 1/20 0.50
DRD3 P35462 1/20 0.50
APP P05067 1/20 0.49
ENPP2 Q13822 1/20 0.47
CYP4F2 P78329 1/20 0.45
CYP4A11 Q02928 1/20 0.45
LMNA P02545 1/20 0.44
CYP1A2 P05177 1/20 0.44
PTGS1 P23219 1/20 0.44
SLC6A2 P23975 1/20 0.44
CYP2C19 P33261 1/20 0.44
PTGS2 P35354 1/20 0.44
SLC6A3 Q01959 1/20 0.44
HIF1A Q16665 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
DRD1 P21728 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14202654 0.88 MAOB (0.53) CYP4F2CYP4A11NR4A2MAOBMEN1
SCHEMBL194419 0.82 TSHR (0.52) APPCYP4F2CYP4A11LMNACYP1A2
SCHEMBL29548398 0.81 APP (0.71) DRD2DRD4ADRA1DADRA1AADRA1B
SCHEMBL384725 0.81 APP (0.71) DRD2DRD4ADRA1DADRA1AADRA1B
SCHEMBL2859448 0.80 CYP3A4 (0.50) DRD2DRD4ADRA1DADRA1AADRA1B
Phenol SCHEMBL28049001 0.79 APP (0.69) DRD2DRD4ADRA1DADRA1AADRA1B
SCHEMBL8716014 0.77 CYP3A4 (0.58) APPENPP2LMNACYP1A2ALDH1A1
SCHEMBL27530842 0.77 CYP3A4 (0.48) DRD2APPENPP2LMNADRD1
Formaldehyde SCHEMBL28868941 0.76 APP (0.65) DRD2DRD4ADRA1DADRA1AADRA1B
SCHEMBL4473780 0.76 MAOA (0.71) MAOBKDM4EALDH1A1PKMRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1180008-C Method for content protection using durable UV absorbers �������⻯ѧƷ�ع����޹�˾ 2004-12-15 CN disclosed
CN-1427866-A Method of content protection with durable UV absorbers CIBA SC HOLDING AG (CH) 2003-07-02 CN disclosed