SCHEMBL2859448

SCHEMBL2859448

Oc1cccc(OOc2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.50
CA12 O43570 3/20 0.50
CA2 P00918 3/20 0.50
CA9 Q16790 3/20 0.50
CA14 Q9ULX7 2/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
CA5A P35218 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
HSD17B1 P14061 2/20 0.47
HSD17B2 P37059 2/20 0.47
CYP1A2 P05177 1/20 0.46
DRD2 P14416 1/20 0.46
DRD4 P21917 1/20 0.46
ADRA1D P25100 1/20 0.46
ADRA1A P35348 1/20 0.46
ADRA1B P35368 1/20 0.46
DRD3 P35462 1/20 0.46
CA1 P00915 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8716014 0.93 CYP3A4 (0.58) CYP3A4CA12CA2CA9CA14
SCHEMBL21393012 0.86 CYP3A4 (0.57) CYP3A4CA12CA2CA9CA14
SCHEMBL450261 0.81 LTA4H (0.62) CYP3A4CA12CA2CA9CA14
SCHEMBL27488691 0.80 DRD2 (0.50) CYP3A4ALDH1A1LMNACYP1A2DRD2
SCHEMBL1174127 0.79 LTA4H (0.60) CYP3A4CA12CA2CA9CA14
SCHEMBL4494616 0.79 CYP3A4 (0.53) CYP3A4CA12CA2CA9CA14
SCHEMBL10337742 0.79 LTA4H (0.60) CYP3A4CA12CA2CA9CA14
SCHEMBL9385056 0.79 LTA4H (0.67) CYP3A4CA12CA2CA9CA14
SCHEMBL11817541 0.79 LTA4H (0.60) CYP3A4CA12CA2CA9CA14
Diphenylether SCHEMBL1252647 0.78 LTA4H (0.65) CYP3A4CA12CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102574992-A Liquid crystalline polymer and molded article POLYPLASTICS CO 2012-07-11 CN disclosed
CN-101611069-B Crystalline resin cured product, crystalline resin composite, and method for producing same NIPPON STEEL CHEMICAL CO 2012-05-30 CN disclosed
US-7713449-B2 Polymer electrolytic material, polymer electrolytic part, membrane electrode assembly, and polymer electrolyte fuel cell TORAY INDUSTRIES, INC. (JP) 2010-05-11 US disclosed
CN-101611069-A Crystalline resin cured product, crystalline resin composite, and method for producing same NIPPON STEEL CHEMICAL CO (JP) 2009-12-23 CN disclosed
CN-100364160-C Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES (JP) 2008-01-23 CN disclosed
US-20060180796-A1 Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES, INC. (JP) 2006-08-17 US disclosed
EP-1619735-A1 POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE PART, MEMBRANE ELECTRODE COMPOSITE AND POLYMER ELECTROLYTE TYPE FUEL CELL TORAY INDUSTRIES, INC. (JP) 2006-01-25 EP disclosed
US-4529565-A Polyester of substituted or unsubstituted phenoxyhydroquinone ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1985-07-16 US disclosed