Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27523181 | 0.98 | ALDH1A1 (0.42) | ALDH1A1LMNACYP1A2KMT2ANPSR1 | |
| SCHEMBL15320289 | 0.76 | CYP2C19 (0.50) | ALDH1A1LMNACYP1A2NPSR1POLB | |
| SCHEMBL15336489 | 0.76 | CYP2C19 (0.50) | ALDH1A1LMNACYP1A2NPSR1POLB | |
| SCHEMBL27525385 | 0.75 | ALDH1A1 (0.45) | ALDH1A1LMNACYP1A2KMT2ANPSR1 | |
| SCHEMBL24394626 | 0.74 | KMT2A (0.46) | ALDH1A1KMT2ANPSR1PTGS2POLB | |
| SCHEMBL10592440 | 0.74 | KMT2A (0.52) | ALDH1A1LMNACYP1A2KMT2APOLB | |
| Hydrochloric Acid SCHEMBL8955579 | 0.73 | ALDH1A1 (0.44) | ALDH1A1LMNACYP1A2KMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL27504701 | 0.73 | ALDH1A1 (0.44) | ALDH1A1LMNACYP1A2KMT2ANPSR1 | |
| SCHEMBL364110 | 0.72 | HDAC3 (0.58) | ALDH1A1LMNAKMT2APOLBTSHR | |
| SCHEMBL828587 | 0.72 | TPH1 (0.55) | CYP1A2NPSR1POLBMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1211370-C | Imidazole derivatives with biphenylsulfonyl substituents, process for their preparation and their use as pharmaceuticals or diagnostic agents | AVENTIS PHARMA GMBH (DE) | 2005-07-20 | — | — | CN | disclosed |
| CN-1326928-A | Biphenyl sulfonyl amino-cyanogen, its preparing method and use as medicine thereof | AVENTIES PHARMACY GMBH (DE) | 2001-12-19 | — | — | CN | disclosed |
| CN-1309645-A | Imidazole derivatives with biphenylsulfonyl substituents, process for their preparation and their use as pharmaceuticals or diagnostic agents | AVENTIS PHARMA GMBH (DE) | 2001-08-22 | — | — | CN | disclosed |
| CN-1212255-A | Biphenylsulfonylcyanamides, method for the production thereof and use thereof as medicaments | HOECHST MARION ROUSSEL DE GMBH (DE) | 1999-03-31 | — | — | CN | disclosed |