Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27502137 | 0.88 | DRD2 (0.39) | DRD2OPRM1DRD3OPRD1OPRK1 | |
| SCHEMBL28230163 | 0.85 | ABAT (0.38) | ABATKLKB1 | |
| SCHEMBL27504309 | 0.85 | ABAT (0.38) | KDM4EALDH1A1ABATKLKB1SMN1; SMN2 | |
| SCHEMBL6883550 | 0.85 | ESR1 (0.43) | DRD2OPRM1DRD3OPRD1OPRK1 | |
| SCHEMBL6875813 | 0.84 | NR1H2 (0.38) | NR1H2NR1H3KDM4EALDH1A1POLB | |
| SCHEMBL10824484 | 0.80 | NPC1 (0.44) | DRD2OPRM1DRD3OPRD1OPRK1 | |
| SCHEMBL27489191 | 0.80 | ABAT (0.53) | DRD2OPRM1DRD3OPRD1OPRK1 | |
| SCHEMBL27487452 | 0.79 | HTR1A (0.41) | NR1H2NR1H3ALDH1A1LMNA | |
| SCHEMBL7815091 | 0.79 | ALDH1A1 (0.43) | DRD2OPRM1DRD3OPRD1OPRK1 | |
| SCHEMBL6882011 | 0.77 | ALDH1A1 (0.44) | DRD2OPRM1DRD3OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100357258-C | Production of keto acids | CIBA SC HOLDING AG (CH) | 2007-12-26 | — | — | CN | disclosed |
| CN-1301962-C | Production of keto acids | CIBA SC HOLDING AG (CH) | 2007-02-28 | — | — | CN | disclosed |
| CN-1575274-A | Production of keto acids | CIBA SC HOLDING AG (CH) | 2005-02-02 | — | — | CN | disclosed |
| CN-1197062-A | Production of keto acids | CIBA SC HOLDING AG (CH) | 1998-10-28 | — | — | CN | disclosed |