Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.51 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | UGCG | Q16739 | 1/20 | 0.38 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716217 | 1.00 | TSHR (0.64) | TSHRALDH1A1TDP1SMN1; SMN2SPHK2 | |
| SCHEMBL27508747 | 1.00 | TSHR (0.64) | TSHRALDH1A1TDP1SMN1; SMN2SPHK2 | |
| SCHEMBL28495305 | 1.00 | TSHR (0.64) | TSHRALDH1A1TDP1SMN1; SMN2SPHK2 | |
| SCHEMBL27487263 | 0.98 | TSHR (0.67) | TSHRALDH1A1TDP1SMN1; SMN2SPHK2 | |
| SCHEMBL3786529 | 0.93 | TSHR (0.63) | TSHRALDH1A1TDP1SMN1; SMN2SPHK2 | |
| SCHEMBL22826269 | 0.91 | TSHR (0.72) | TSHRALDH1A1TDP1SMN1; SMN2SPHK2 | |
| SCHEMBL20579953 | 0.87 | TSHR (0.59) | TSHRALDH1A1TDP1SMN1; SMN2SPHK2 | |
| SCHEMBL8671256 | 0.85 | ALDH1A1 (0.62) | TSHRALDH1A1TDP1SMN1; SMN2SPHK2 | |
| SCHEMBL8671443 | 0.85 | ALDH1A1 (0.62) | TSHRALDH1A1TDP1SMN1; SMN2SPHK2 | |
| SCHEMBL8676128 | 0.85 | ALDH1A1 (0.62) | TSHRALDH1A1TDP1SMN1; SMN2SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1165510-A | Amine derivatives | KAO CORP (JP) | 1997-11-19 | — | — | CN | disclosed |