Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716217 | 0.98 | TSHR (0.64) | TSHRALDH1A1TDP1SMN1; SMN2SPHK2 | |
| SCHEMBL27508747 | 0.98 | TSHR (0.64) | TSHRALDH1A1TDP1SMN1; SMN2SPHK2 | |
| SCHEMBL27489352 | 0.98 | TSHR (0.64) | TSHRALDH1A1TDP1SMN1; SMN2SPHK2 | |
| SCHEMBL28495305 | 0.98 | TSHR (0.64) | TSHRALDH1A1TDP1SMN1; SMN2SPHK2 | |
| SCHEMBL22826269 | 0.92 | TSHR (0.72) | TSHRALDH1A1TDP1SMN1; SMN2SPHK2 | |
| SCHEMBL3786529 | 0.91 | TSHR (0.63) | TSHRALDH1A1TDP1SMN1; SMN2SPHK2 | |
| SCHEMBL20579953 | 0.85 | TSHR (0.59) | TSHRALDH1A1TDP1SMN1; SMN2SPHK2 | |
| SCHEMBL8672600 | 0.84 | ALDH1A1 (0.64) | TSHRALDH1A1TDP1SMN1; SMN2SPHK2 | |
| SCHEMBL19051883 | 0.84 | TSHR (0.78) | TSHRALDH1A1TDP1SMN1; SMN2SPHK2 | |
| SCHEMBL23668239 | 0.84 | TSHR (0.95) | TSHRALDH1A1TDP1SMN1; SMN2SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1165510-A | Amine derivatives | KAO CORP (JP) | 1997-11-19 | — | — | CN | disclosed |