Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | VDR | P11473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27595828 | 0.98 | ALDH1A1 (0.41) | ALDH1A1CYP2C19HTTL3MBTL1KCNB1 | |
| SCHEMBL27595814 | 0.81 | ALDH1A1 (0.41) | ALDH1A1CYP2C19CYP3A4HPGDKDM4E | |
| SCHEMBL27489421 | 0.77 | MAPT (0.37) | HTTL3MBTL1KDM4EKMT2ALMNA | |
| SCHEMBL27595777 | 0.77 | HTT (0.42) | ALDH1A1HTTL3MBTL1HPGDLMNA | |
| SCHEMBL27614667 | 0.76 | KDM4E (0.31) | L3MBTL1CYP3A4KDM4ESMN1; SMN2 | |
| SCHEMBL27595800 | 0.75 | MAPT (0.38) | HTTL3MBTL1KDM4EKMT2ALMNA | |
| SCHEMBL27507082 | 0.75 | CYP3A4 (0.45) | CYP2C19CYP3A4KDM4EMEN1KMT2A | |
| SCHEMBL27595773 | 0.75 | L3MBTL1 (0.42) | ALDH1A1CYP2C19HTTL3MBTL1HPGD | |
| SCHEMBL27595847 | 0.73 | RAB9A (0.39) | ALDH1A1L3MBTL1HPGDKDM4EMEN1 | |
| SCHEMBL27614450 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1198831-C | Organic metal monoacylalkylphosphine compound | CIBA SC HOLDING AG (CH) | 2005-04-27 | — | — | CN | disclosed |
| CN-1329005-A | Organic metal monoacylalkylphosphine compound | CIBA SC HOLDING AG (CH) | 2002-01-02 | — | — | CN | disclosed |