Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | GALK1 | P51570 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14710459 | 0.72 | HTT (0.75) | SMN1; SMN2HTTMAPK10HSD17B10RAB9A | |
| SCHEMBL16268584 | 0.70 | HTT (0.65) | SMN1; SMN2HTTMAPK10TSHRHSD17B10 | |
| SCHEMBL17781303 | 0.70 | SMN1; SMN2 (0.53) | SMN1; SMN2HTTMAPK10TSHRHSD17B10 | |
| SCHEMBL942577 | 0.69 | PDE4D (0.56) | SMN1; SMN2HTTMAPK10HSD17B10RAB9A | |
| SCHEMBL600955 | 0.69 | PDE4D (0.71) | SMN1; SMN2HTTMAPK10HSD17B10RAB9A | |
| SCHEMBL8529906 | 0.68 | ALOX5 (0.52) | SMN1; SMN2HTTMAPK10TSHRHSD17B10 | |
| SCHEMBL11160154 | 0.68 | SMN1; SMN2 (0.55) | SMN1; SMN2HTTMAPK10HSD17B10RAB9A | |
| SCHEMBL2002577 | 0.68 | TSHR (0.67) | MAPK10TSHRHSD17B10KDM4ETP53 | |
| SCHEMBL30385424 | 0.68 | TSHR (0.67) | MAPK10TSHRHSD17B10KDM4ETP53 | |
| SCHEMBL25194957 | 0.68 | CA12 (0.56) | SMN1; SMN2HTTTSHRHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1120837-A | Pyrazole derivatives | NISSAN CHEMICAL IND LTD (JP) | 1996-04-17 | — | — | CN | disclosed |