Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16268639 | 0.80 | ALDH1A1 (0.44) | HTTSMN1; SMN2MAPK10ALDH1A1HSD17B10 | |
| SCHEMBL14710459 | 0.80 | HTT (0.75) | HTTSMN1; SMN2MAPK10HSD17B10PDE4D | |
| SCHEMBL31412612 | 0.73 | ALPL (0.66) | SMN1; SMN2ALDH1A1KMT2ATP53RAB9A | |
| SCHEMBL600955 | 0.72 | PDE4D (0.71) | HTTSMN1; SMN2MAPK10ALDH1A1HSD17B10 | |
| SCHEMBL942577 | 0.72 | PDE4D (0.56) | HTTSMN1; SMN2MAPK10ALDH1A1HSD17B10 | |
| SCHEMBL11160154 | 0.70 | SMN1; SMN2 (0.55) | HTTSMN1; SMN2MAPK10ALDH1A1HSD17B10 | |
| SCHEMBL27489531 | 0.70 | SMN1; SMN2 (0.55) | HTTSMN1; SMN2MAPK10ALDH1A1HSD17B10 | |
| SCHEMBL6305895 | 0.70 | CA12 (0.53) | HTTSMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL20709978 | 0.69 | SMN1; SMN2 (0.53) | HTTSMN1; SMN2MAPK10ALDH1A1HSD17B10 | |
| SCHEMBL17781303 | 0.69 | SMN1; SMN2 (0.53) | HTTSMN1; SMN2MAPK10ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3003042-A1 | HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014191301-A1 | HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2014-12-04 | — | — | WO | disclosed |