Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921589 | 0.91 | AKT1 (0.46) | CTSKATM | |
| SCHEMBL8923100 | 0.91 | AKT1 (0.46) | CTSKATM | |
| SCHEMBL8920403 | 0.91 | AKT1 (0.46) | CTSKATM | |
| SCHEMBL27463518 | 0.86 | HDAC1 (0.46) | — | |
| SCHEMBL27962256 | 0.79 | CTSK (0.56) | CTSKCTSSATM | |
| SCHEMBL10981741 | 0.79 | CTSK (0.62) | CTSKCTSSATM | |
| SCHEMBL28733236 | 0.79 | CTSK (0.62) | CTSKCTSSATM | |
| SCHEMBL10974978 | 0.79 | CTSK (0.62) | CTSKCTSSATM | |
| SCHEMBL27962221 | 0.77 | CTSK (0.54) | CTSKCTSSATM | |
| SCHEMBL8920576 | 0.77 | CTSS (0.50) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1148378-C | 15-deoxyspergualin analogs, their method of preparation and their use in therapeutics | �Ҵ���˾ | 2004-05-05 | — | — | CN | disclosed |
| CN-1119191-A | 15-deoxyspergualin analogs, their method of preparation and their use in therapeutics | FOURNIER IND & SANTE (FR) | 1996-03-27 | — | — | CN | disclosed |