Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923100 | 1.00 | AKT1 (0.46) | AKT1CTSKKLK5ATM | |
| SCHEMBL8921589 | 1.00 | AKT1 (0.46) | AKT1CTSKKLK5ATM | |
| SCHEMBL27489595 | 0.91 | CTSK (0.46) | CTSKATM | |
| SCHEMBL8920576 | 0.86 | CTSS (0.50) | AKT1CTSK | |
| SCHEMBL8920572 | 0.86 | CTSS (0.50) | AKT1CTSK | |
| SCHEMBL8920449 | 0.86 | CTSK (0.47) | AKT1CTSK | |
| SCHEMBL8398725 | 0.85 | HDAC3 (0.45) | — | |
| SCHEMBL8921583 | 0.83 | MAPT (0.48) | AKT1CTSKKLK5 | |
| SCHEMBL8921567 | 0.83 | SMN1; SMN2 (0.47) | AKT1CTSK | |
| SCHEMBL24326687 | 0.80 | AKT1 (0.47) | AKT1CTSKKLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637613-A | ANTITUMOR AGENT; IMMUNOSUPPRESSANTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1997-06-10 | — | — | US | disclosed |