Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1908280 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10POLBNPC1 | |
| SCHEMBL1314931 | 0.73 | CYP11B1 (0.56) | KDM4EALDH1A1HSD17B10POLBNPC1 | |
| SCHEMBL27490294 | 0.73 | ALDH1A1 (0.45) | KDM4EALDH1A1HSD17B10POLBNPC1 | |
| SCHEMBL2040756 | 0.73 | KDM4E (0.45) | KDM4EALDH1A1HSD17B10POLBNPC1 | |
| Potassium SCHEMBL8852787 | 0.70 | CYP11B1 (0.52) | KDM4EALDH1A1POLBNPC1RAB9A | |
| SCHEMBL15638530 | 0.69 | ALDH1A1 (0.44) | KDM4EALDH1A1HSD17B10POLBNPC1 | |
| SCHEMBL859147 | 0.68 | — | — | |
| SCHEMBL12596380 | 0.66 | KDM4E (0.65) | KDM4EALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL5757978 | 0.65 | DPP4 (0.51) | KDM4EALDH1A1HSD17B10POLBNPC1 | |
| SCHEMBL1907032 | 0.65 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1177350-A | Imidazole derivatives and pharmaceutical compositions thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1998-03-25 | — | — | CN | disclosed |