SCHEMBL27490451

SCHEMBL27490451

[CH2]c1cccc(F)c1.[MgH2]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26517 0.97
SCHEMBL27563263 0.94
Zinc Chloride SCHEMBL28067943 0.87 ACHE (0.41)
SCHEMBL28737718 0.87 ACHE (0.41)
Magnesium Chloride Anhydrous SCHEMBL28476554 0.87 ACHE (0.41)
SCHEMBL27522230 0.87 ACHE (0.41)
SCHEMBL2095994 0.82 TAAR1 (0.54)
SCHEMBL5541876 0.77 MMP2 (0.40)
SCHEMBL10546679 0.77 HAO1 (0.46)
Ethylene SCHEMBL27888003 0.76 ACHE (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1626534-A Steroid receptor modulator compounds and methods LIGAND PHARM INC (US) 2005-06-15 CN disclosed
CN-1547570-A Substituted c-cyclohexylmethylamine derivatives 2004-11-17 CN disclosed
CN-1172917-C Steroid receptor modulator compounds and methods ��λ��ҩ��ɷ����޹�˾ 2004-10-27 CN disclosed
CN-1476429-A EP4 receptor selective agonists in treatment of osteoporosis �Ʒ� 2004-02-18 CN disclosed
CN-1175247-A Steroid receptor modulator compounds and methods LIGAND PHARM INC (US) 1998-03-04 CN disclosed