Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26517 | 0.90 | — | — | |
| SCHEMBL27563263 | 0.87 | — | — | |
| SCHEMBL27490451 | 0.87 | — | — | |
| SCHEMBL27522230 | 0.86 | ACHE (0.41) | ACHENFE2L2TAAR1CES2CES1 | |
| Zinc Chloride SCHEMBL28067943 | 0.86 | ACHE (0.41) | ACHENFE2L2TAAR1CES2CES1 | |
| SCHEMBL28737718 | 0.81 | ACHE (0.41) | ACHENFE2L2TAAR1CES2CES1 | |
| SCHEMBL2095994 | 0.76 | TAAR1 (0.54) | ACHENFE2L2TAAR1CYP3A4ESR2 | |
| SCHEMBL5541876 | 0.76 | MMP2 (0.40) | NFE2L2 | |
| Magnesium Chloride Anhydrous SCHEMBL27760910 | 0.73 | ALDH1A1 (0.42) | TAAR1CYP3A4CHRM5PARP1IDO1 | |
| Magnesium Chloride Anhydrous SCHEMBL27843279 | 0.71 | ACHE (0.50) | ACHETAAR1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250034125-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2025-01-30 | — | — | US | disclosed |
| CN-111943886-B | Substituted pyridine compound and preparation method thereof | 华中师范大学 | 2022-02-08 | — | — | CN | disclosed |
| CN-113906019-A | Compound and use thereof | 优曼尼蒂治疗公司 | 2022-01-07 | — | — | CN | disclosed |
| CN-111961045-A | Synthesis method of 1, 6-naphthyridine-4 (1H) -ketone compound | 南京纳丁菲医药科技有限公司 | 2020-11-20 | — | — | CN | disclosed |
| CN-111943886-A | Substituted pyridine compound and preparation method thereof | 华中师范大学 | 2020-11-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250034125-A1 | COMPOUNDS AND USES THEREOF | NLN, BDNF, NQO1 | ACHE 13/4885NFE2L2 142/4885TAAR1 3815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.