Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27461054 | 0.80 | HTT (0.42) | MAPK8NPC1MEN1NR1I2LMNA | |
| SCHEMBL4139670 | 0.71 | CDK1 (0.40) | PTGS1PTGS2CA12CA1CA2 | |
| SCHEMBL598441 | 0.67 | CYP2D6 (0.43) | PTGS1PTGS2NPC1LMNACYP3A4 | |
| SCHEMBL808604 | 0.63 | CDK1 (0.47) | TLR7NPC1LMNA | |
| SCHEMBL9065880 | 0.63 | LTA4H (0.42) | MAPK8PTGS1PTGS2TSHRTLR7 | |
| SCHEMBL11270818 | 0.63 | LTA4H (0.42) | MAPK8PTGS1PTGS2TSHRTLR7 | |
| SCHEMBL28844151 | 0.62 | MEN1 (0.39) | MAPK8MEN1LMNAMAPTKMT2A | |
| SCHEMBL28110847 | 0.62 | LMNA (0.30) | LMNA | |
| SCHEMBL17584792 | 0.61 | LTA4H (0.41) | PTGS1PTGS2NPC1MEN1CYP3A4 | |
| SCHEMBL899058 | 0.61 | NR5A1 (0.43) | MAPK8TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1210460-A | Preparations stimulating nail growth | HOECHST AG (DE) | 1999-03-10 | — | — | CN | claimed |
| CN-1239157-C | Formulation for promoting nail growth | SANOFFY AVENTIS DEUTSCHLAND GM (DE) | 2006-02-01 | — | — | CN | disclosed |
| CN-1210460-A | Preparations stimulating nail growth | HOECHST AG (DE) | 1999-03-10 | — | — | CN | disclosed |