SCHEMBL27490702

SCHEMBL27490702

CCC(=O)CC.O=[N+]([O-])c1ccccc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
SMN1; SMN2 Q16637 3/20 0.49
NPC1 O15118 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C19 P33261 1/20 0.49
RAB9A P51151 1/20 0.49
LMNA P02545 3/20 0.48
HPGD P15428 1/20 0.47
VCAM1 P19320 2/20 0.46
MAPT P10636 2/20 0.45
MAPK1 P28482 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
TSHR P16473 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CTSD P07339 1/20 0.44
GAA P10253 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL27346899 0.85 HPGD (0.53) ALDH1A1MEN1KMT2ASMN1; SMN2NPC1
Methyl Alcohol SCHEMBL28906975 0.85 HPGD (0.56) ALDH1A1MEN1KMT2ASMN1; SMN2NPC1
Acetic Acid SCHEMBL11038126 0.84 VCAM1 (0.54) ALDH1A1MEN1KMT2ASMN1; SMN2NPC1
SCHEMBL78743 0.83 HPGD (0.62) ALDH1A1MEN1KMT2ASMN1; SMN2NPC1
SCHEMBL29962795 0.83 HPGD (0.62) ALDH1A1MEN1KMT2ASMN1; SMN2NPC1
SCHEMBL27873887 0.83 HPGD (0.62) ALDH1A1MEN1KMT2ASMN1; SMN2NPC1
Ethylene Glycol SCHEMBL11649051 0.82 ALDH1A1 (0.55) ALDH1A1MEN1KMT2ASMN1; SMN2NPC1
SCHEMBL28290876 0.81 HPGD (0.56) ALDH1A1MEN1KMT2ASMN1; SMN2NPC1
Methylamine SCHEMBL28051837 0.81 HPGD (0.56) ALDH1A1MEN1KMT2ASMN1; SMN2NPC1
Selenium SCHEMBL10603347 0.81 HPGD (0.60) ALDH1A1MEN1KMT2ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1181065-C Aralkylformylalkyl piperazine derivative and its application as brain nerve protector �Ϻ�ҽҩ��ҵ�о�Ժ 2004-12-22 CN disclosed
CN-1381448-A Aralkylformylalkyl piperazine derivative and its application as brain nerve protector SHANGHAI ACADEMY OF MEDICAL IN (CN) 2002-11-27 CN disclosed