SCHEMBL27490756

SCHEMBL27490756

C=Cc1ccc(CC(OC)OC)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
TRPA1 O75762 1/20 0.36
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA7 P36544 1/20 0.36
CHRNA4 P43681 1/20 0.36
TSHR P16473 2/20 0.36
TAS1R3 Q7RTX0 2/20 0.36
TAS1R1 Q7RTX1 2/20 0.36
HDAC8 Q9BY41 1/20 0.35
TP53 P04637 2/20 0.35
CYP3A4 P08684 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SLC6A4 P31645 1/20 0.34
MIF P14174 1/20 0.34
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29268616 0.80 ALDH1A1 (0.38) ALDH1A1TRPA1CHRNB2CHRNB4CHRNA3
SCHEMBL546949 0.78 ALDH1A1 (0.50) ALDH1A1TSHRSMN1; SMN2
SCHEMBL5197835 0.78 ALDH1A1 (0.44) ALDH1A1TRPA1CHRNB2CHRNB4CHRNA3
SCHEMBL4557206 0.78 ALDH1A1 (0.44) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL14336225 0.77 ALDH1A1 (0.39) ALDH1A1TRPA1CHRNB2CHRNB4CHRNA3
SCHEMBL570118 0.77 ALDH1A1 (0.48) ALDH1A1TRPA1CHRNB2CHRNB4CHRNA3
Ammonia Solution, Strong SCHEMBL28640315 0.77 ALDH1A1 (0.48) ALDH1A1TSHRSMN1; SMN2
SCHEMBL24146430 0.76 ALDH1A1 (0.52) ALDH1A1TRPA1CHRNB2CHRNB4CHRNA3
SCHEMBL3677179 0.75 ALDH1A1 (0.46) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL891582 0.75 ALDH1A1 (0.46) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1213343-A Recording sheet and process for production thereof DAICEL CHEM (JP) 1999-04-07 CN disclosed