Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2539829 | 0.84 | KDM4E (0.60) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL27491756 | 0.81 | KDM4E (0.71) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL27507137 | 0.80 | MAPT (0.58) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL29281760 | 0.77 | KDM4E (0.62) | KDM4EALDH1A1HPGDF2GLA | |
| SCHEMBL830265 | 0.76 | SMN1; SMN2 (0.48) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL29420513 | 0.76 | SMN1; SMN2 (0.48) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL2531203 | 0.74 | POLB (0.62) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL9055047 | 0.74 | ALDH1A1 (0.71) | KDM4EALDH1A1HPGDF2GLA | |
| SCHEMBL16742685 | 0.73 | ALDH1A1 (0.52) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL1289610 | 0.73 | BCHE (0.51) | KDM4EALDH1A1POLBHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1193016-C | Process for synthesizing inhibitor of phosphatidase A2 | UNIV BEIJING (CN) | 2005-03-16 | — | — | CN | disclosed |
| CN-1502609-A | Process for synthesizing inhibitor of phosphatidase A2 | 北京大学 | 2004-06-09 | — | — | CN | disclosed |