Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GGT1 | P19440 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4274235 | 0.83 | ALDH1A1 (0.53) | MAPTALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL28041155 | 0.80 | LMNA (0.65) | MAPTALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL27810074 | 0.80 | MAPT (0.49) | MAPTALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL27491071 | 0.80 | KDM4E (0.51) | MAPTALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL2539705 | 0.78 | HPGD (0.62) | MAPTALDH1A1KDM4EHTTHPGD | |
| SCHEMBL27508841 | 0.78 | KDM4E (0.50) | MAPTALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL28598438 | 0.77 | HPGD (0.60) | MAPTALDH1A1KDM4EHTTHPGD | |
| SCHEMBL13209738 | 0.76 | KDM4E (0.69) | MAPTALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL9780451 | 0.75 | KDM4E (0.56) | MAPTALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL57542 | 0.75 | KDM4E (0.69) | MAPTALDH1A1KDM4EHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102099352-A | STAT3 inhibitor containing quinolinecarboxamide derivative as active ingredient | PHARMA IP GENERAL INC ASS | 2011-06-15 | — | — | CN | disclosed |
| CN-1193016-C | Process for synthesizing inhibitor of phosphatidase A2 | UNIV BEIJING (CN) | 2005-03-16 | — | — | CN | disclosed |
| CN-1502609-A | Process for synthesizing inhibitor of phosphatidase A2 | 北京大学 | 2004-06-09 | — | — | CN | disclosed |