Sugi Predict

Sugi Predict / Compounds / SCHEMBL9055047

SCHEMBL9055047

SCHEMBL9055047

COc1ccc(C=O)c(OC(C)=O)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.71
▸ TRIM24 O15164 1/20 0.59
▸ TYR P14679 1/20 0.59
▸ TRIM33 Q9UPN9 1/20 0.59
▸ ERN1 O75460 2/20 0.54
▸ BACE1 P56817 1/20 0.54
▸ MAPT P10636 4/20 0.53
▸ MEN1 O00255 1/20 0.53
▸ KMT2A Q03164 1/20 0.53
▸ HPGD P15428 2/20 0.53
▸ F2 P00734 1/20 0.53
▸ GLA P06280 1/20 0.53
▸ CYP1A2 P05177 2/20 0.50
▸ CYP1A1 P04798 1/20 0.50
▸ CYP1B1 Q16678 1/20 0.50
▸ TUBB4A P04350 1/20 0.48
▸ TUBB P07437 1/20 0.48
▸ TUBA3C P0DPH7 1/20 0.48
▸ TUBA1B P68363 1/20 0.48
▸ TUBA4A P68366 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3829716 0.89 KDM4E (0.59) ALDH1A1TRIM24TYRTRIM33BACE1
SCHEMBL4644522 0.88 ALDH1A1 (0.59) ALDH1A1TRIM24TYRTRIM33ERN1
SCHEMBL16111393 0.88 ALDH1A1 (0.73) ALDH1A1TRIM24TYRTRIM33ERN1
SCHEMBL16046208 0.86 ALDH1A1 (0.71) ALDH1A1TRIM24TYRTRIM33ERN1
SCHEMBL3292760 0.86 ALDH1A1 (0.71) ALDH1A1TRIM24TYRTRIM33ERN1
SCHEMBL9055043 0.85 ALDH1A1 (0.65) ALDH1A1TRIM24TYRTRIM33ERN1
SCHEMBL13168673 0.85 ALDH1A1 (0.69) ALDH1A1TRIM24TYRTRIM33ERN1
SCHEMBL96291 0.83 ALDH1A1 (1.00) ALDH1A1TRIM24TYRTRIM33ERN1
SCHEMBL15052052 0.83 MAPT (0.61) ALDH1A1MAPTMEN1KMT2AHPGD
SCHEMBL6131805 0.82 ALDH1A1 (0.65) ALDH1A1TRIM24TYRTRIM33ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3959189-B1 METHOD OF DEPOLYMERISING PHENOLIC POLYMERS UNIV STELLENBOSCH (ZA) 2026-01-28 — — EP disclosed
US-20250382303-A1 NOVEL COMPOUND AS NADPH OXIDASE 2 INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING SAME DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2025-12-18 — — US disclosed
EP-4549441-A1 NOVEL COMPOUND AS NADPH OXIDASE 2 INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Dongguk University Industry-Academic Cooperation Foundation (KR) 2025-05-07 — — EP disclosed
US-12275697-B2 Method of depolymerising phenolic polymers STELLENBOSCH UNIVERSITY (ZA) 2025-04-15 — — US disclosed
US-20250113823-A1 Arthropod Control Compositions FIRMENICH SA (CH) 2025-04-10 — — US disclosed
EP-4444095-A1 ARTHROPOD CONTROL COMPOSITIONS Firmenich SA (CH) 2024-10-16 — — EP disclosed
CN-118591291-A Arthropod control composition 弗门尼舍有限公司 2024-09-03 — — CN disclosed
US-12060362-B2 Inhibitors of glucose transporters (GLUTs) LEAD DISCOVERY CENTER GMBH (DE) 2024-08-13 — — US disclosed
WO-2024005526-A1 NOVEL COMPOUND AS NADPH OXIDASE 2 INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 동국대학교 산학협력단 2024-01-04 — — WO disclosed
WO-2023139053-A1 ARTHROPOD CONTROL COMPOSITIONS FIRMENICH SA (CH) 2023-07-27 — — WO disclosed
EP-3814359-B1 INHIBITORS OF GLUCOSE TRANSPORTERS (GLUTS) LEAD DISCOVERY CENTER GMBH (DE) 2022-08-17 — — EP disclosed
US-20220227694-A1 Method of Depolymerising Phenolic Polymers STELLENBOSCH UNIVERSITY (ZA) 2022-07-21 — — US disclosed
EP-3959189-A1 METHOD OF DEPOLYMERISING PHENOLIC POLYMERS Stellenbosch University (ZA) 2022-03-02 — — EP disclosed
US-20210198269-A1 INHIBITORS OF GLUCOSE TRANSPORTERS (GLUTs) MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2021-07-01 — — US disclosed
US-20210198269-A1 INHIBITORS OF GLUCOSE TRANSPORTERS (GLUTs) MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2021-07-01 — — US disclosed
EP-3814359-A1 INHIBITORS OF GLUCOSE TRANSPORTERS (GLUTS) Lead Discovery Center GmbH (DE) 2021-05-05 — — EP disclosed
WO-2020217209-A1 METHOD OF DEPOLYMERISING PHENOLIC POLYMERS STELLENBOSCH UNIVERSITY (ZA) 2020-10-29 — — WO disclosed
WO-1996012706-A1 NOVEL ACID PYRAZOLE AND PYRAZOLONE DERIVATIVES FOR USE AS ENDOTHELIN RECEPTOR ANTAGONISTS ROUSSEL UCLAF (FR) 1996-05-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220227694-A1 Method of Depolymerising Phenolic Polymers DCXR, GRHPR, HPD ALDH1A1 2402/4885TRIM24 2839/4885TYR 17/4885
US-12060362-B2 Inhibitors of glucose transporters (GLUTs) SLC2A1, SLC2A3, SLC2A4 ALDH1A1 364/4885TRIM24 3386/4885TYR 1874/4885
US-12275697-B2 Method of depolymerising phenolic polymers DCXR, GRHPR, HPD ALDH1A1 2402/4885TRIM24 2839/4885TYR 17/4885
US-20250113823-A1 Arthropod Control Compositions AGO2, EXOSC9, C5 ALDH1A1 3700/4885TRIM24 3180/4885TYR 35/4885
US-20210198269-A1 INHIBITORS OF GLUCOSE TRANSPORTERS (GLUTs) SLC2A1, SLC2A3, SLC2A4 ALDH1A1 515/4885TRIM24 3650/4885TYR 1978/4885
US-20250382303-A1 NOVEL COMPOUND AS NADPH OXIDASE 2 INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING SAME CYBB, NOX4, NOX1 ALDH1A1 565/4885TRIM24 2521/4885TYR 300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.