Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 4/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ALPG | P10696 | 2/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | OGG1 | O15527 | 1/20 | 0.37 |
| ▸ | AOC2 | O75106 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798325 | 0.81 | KDM6B (0.42) | ALPLKDM6BKDM4AKDM5AALDH1A1 | |
| SCHEMBL6507956 | 0.80 | HCAR2 (0.46) | ALPLDAOHCAR2NTRK1KMT2A | |
| SCHEMBL12174907 | 0.78 | HCAR2 (0.47) | ALPLDAOHCAR2NTRK1KMT2A | |
| SCHEMBL877436 | 0.78 | HCAR2 (0.52) | ALPLDAOHCAR2ALDH1A1KDM4E | |
| SCHEMBL3587984 | 0.77 | KDM4E (0.48) | ALPLDAOHCAR2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL1371875 | 0.77 | HCAR2 (0.50) | ALPLDAOHCAR2ALDH1A1KDM4E | |
| SCHEMBL2828750 | 0.76 | ALDH1A1 (0.41) | ALPLDAOHCAR2KDM6BKDM4A | |
| SCHEMBL12158535 | 0.74 | HCAR2 (0.43) | ALPLDAOHCAR2NTRK1KMT2A | |
| SCHEMBL16027471 | 0.73 | ALPL (0.61) | ALPLDAOHCAR2ALDH1A1MEN1 | |
| SCHEMBL8720083 | 0.72 | SMN1; SMN2 (0.51) | DAOHCAR2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1209807-A | 1-pyrazol-3-yl-ethyl-4-indol-3-yl piperdine as medicine acting on central nervous system | MERCK PATENT AG (DE) | 1999-03-03 | — | — | CN | disclosed |