Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.36 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27490240 | 0.93 | ALK (0.35) | NR1H2NR1H3ALKMAPT | |
| SCHEMBL27475645 | 0.86 | PDK2 (0.34) | NR1H2NR1H3 | |
| SCHEMBL7847221 | 0.83 | HDAC4 (0.43) | EPHX2HDAC4MAPT | |
| SCHEMBL6197879 | 0.82 | ITGB2 (0.45) | — | |
| SCHEMBL6201497 | 0.78 | ITGAL (0.34) | NR1H2NR1H3EPHX2HDAC4HDAC6 | |
| SCHEMBL7617894 | 0.78 | ITGB2 (0.42) | NR1H2NR1H3MMP1MMP3MMP7 | |
| SCHEMBL6201492 | 0.77 | ABHD6 (0.35) | NR1H2NR1H3HDAC6MCL1SFRP1 | |
| SCHEMBL28761889 | 0.76 | MAPT (0.39) | MAPT | |
| SCHEMBL6199011 | 0.75 | ITGB2 (0.41) | MAPT | |
| SCHEMBL1849268 | 0.73 | NR1H2 (0.54) | NR1H2NR1H3EPHX2SETD7PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1192018-C | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-03-09 | — | — | CN | claimed |
| CN-1353691-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-06-12 | — | — | CN | claimed |
| CN-1350520-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-05-22 | — | — | CN | claimed |
| CN-1955164-A | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LAB (US) | 2007-05-02 | — | — | CN | disclosed |
| CN-1680338-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-10-12 | — | — | CN | disclosed |
| CN-1192018-C | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-03-09 | — | — | CN | disclosed |
| CN-1353691-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-06-12 | — | — | CN | disclosed |
| CN-1350520-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-05-22 | — | — | CN | disclosed |