Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21070695 | 0.79 | KDM4E (0.42) | CREBBPALDH1A1KDM4ETUBB4ATUBB | |
| SCHEMBL31664088 | 0.79 | KDM4E (0.42) | CREBBPALDH1A1KDM4ETUBB4ATUBB | |
| Ethoxycarbonyl Group SCHEMBL27490855 | 0.79 | CREBBP (0.44) | CREBBPTRPM5ALDH1A1TUBB4ATUBB | |
| Ethoxycarbonyl Group SCHEMBL27474750 | 0.76 | CNR1 (0.48) | CREBBPTRPM5ALDH1A1TUBB4ATUBB | |
| SCHEMBL21070644 | 0.76 | ALDH1A1 (0.40) | CREBBPALDH1A1KDM4ETUBB4ATUBB | |
| SCHEMBL13261931 | 0.75 | ALDH1A1 (0.54) | CREBBPALDH1A1KDM4EHTR2AHTR2C | |
| Ethoxycarbonyl Group SCHEMBL27490462 | 0.74 | TRPM5 (0.39) | TRPM5HTR2AHTR2C | |
| SCHEMBL7954133 | 0.70 | F10 (0.53) | ALDH1A1KDM4EHRH1NLRP3 | |
| SCHEMBL12543380 | 0.69 | HTR2C (0.54) | TRPM5HTR2AHTR2CMCL1CNR1 | |
| SCHEMBL399775 | 0.68 | MAPT (0.58) | CREBBPTRPM5ALDH1A1KDM4ETUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161334-A | Novel substd. guanidine derivs., process for prodn. thereof, and pharmaceutical uses thereof | SUMITOMO PHARMA (JP) | 1997-10-08 | — | — | CN | disclosed |