Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 7/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28741367 | 0.80 | GUSB (0.37) | MEN1USP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27524768 | 0.75 | GUSB (0.37) | MEN1USP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4830718 | 0.74 | SLC6A4 (0.51) | SLC6A4HTR1AHTR1DHTR1B | |
| SCHEMBL12720716 | 0.72 | SPR (0.63) | MEN1CYP1A2CYP3A4CYP2D6KMT2A | |
| SCHEMBL6361928 | 0.71 | SLC6A4 (0.63) | SLC6A4CYP2C19CDK2HTR1A | |
| SCHEMBL14297198 | 0.70 | MTNR1A (0.54) | MEN1USP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4351901 | 0.70 | SLC6A4 (0.69) | SLC6A4HTR1A | |
| SCHEMBL30468389 | 0.70 | SLC6A4 (0.69) | SLC6A4HTR1A | |
| SCHEMBL6879916 | 0.70 | SLC6A4 (0.69) | SLC6A4HTR1A | |
| SCHEMBL27842093 | 0.69 | SLC6A4 (0.64) | SLC6A4DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |