Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | SI | P14410 | 3/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27524768 | 0.93 | GUSB (0.37) | GUSBMEN1USP2CYP1A2CYP3A4 | |
| SCHEMBL27494526 | 0.86 | ALDH1A1 (0.42) | LMNAALDH1A1 | |
| SCHEMBL27494914 | 0.85 | MMP1 (0.40) | GUSBMGAMGAASIMGAM2 | |
| SCHEMBL27532210 | 0.81 | SNCA (0.41) | GUSBMGAMGAASIMGAM2 | |
| SCHEMBL27510950 | 0.81 | TDO2 (0.42) | LMNAALDH1A1 | |
| SCHEMBL27493698 | 0.80 | SLC6A4 (0.47) | MEN1USP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27557415 | 0.78 | GAA (0.40) | GUSBGAAMEN1CYP1A2KMT2A | |
| SCHEMBL28741365 | 0.74 | MGAM (0.41) | GUSBMGAMGAASIMGAM2 | |
| SCHEMBL27495318 | 0.74 | GUSB (0.39) | GUSBMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL27510621 | 0.73 | ITGB3 (0.48) | GAAMEN1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |