Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 3/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27478897 | 0.85 | TSHR (0.34) | MAOAMAOBBCHECCNB2CDK1 | |
| SCHEMBL6936315 | 0.84 | TSHR (0.41) | MAOAMAOBCCNB2CDK1CDK4 | |
| SCHEMBL27849658 | 0.83 | ENPP2 (0.45) | ALDH1A1 | |
| SCHEMBL8693638 | 0.80 | NR4A2 (0.51) | MEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL10750641 | 0.77 | TSHR (0.35) | MAOAMAOBCCNB2CDK1CDK4 | |
| SCHEMBL7304372 | 0.75 | CYP1A2 (0.44) | MEN1LMNAMAPTKMT2ATSHR | |
| SCHEMBL5614230 | 0.74 | TSHR (0.36) | MAOAMAOBCCNB2CDK1CDK4 | |
| SCHEMBL9005245 | 0.74 | MAOA (0.43) | MAOAMAOBCCNB2CDK1CDK4 | |
| SCHEMBL3365736 | 0.73 | TSHR (0.33) | MAOAMAOBCCNB2CDK1CDK4 | |
| SCHEMBL7404744 | 0.73 | MAOA (0.47) | MAOAMAOBCCNB2CDK1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1177343-A | Cell adhesion inhibitors | BIOGEN INC (US) | 1998-03-25 | — | — | CN | claimed |
| CN-1192015-C | Cell adhesion inhibitors | BIOGEN INC (US) | 2005-03-09 | — | — | CN | disclosed |
| CN-1177343-A | Cell adhesion inhibitors | BIOGEN INC (US) | 1998-03-25 | — | — | CN | disclosed |