Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | PPM1D | O15297 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27495608 | 0.85 | AOC1 (0.35) | IDO1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL6674456 | 0.82 | IDO1 (0.38) | IDO1HDAC8MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6675350 | 0.81 | IDO1 (0.37) | IDO1HDAC8SMN1; SMN2MAPTNPC1 | |
| SCHEMBL27493974 | 0.81 | AOC1 (0.33) | HDAC8HTTHDAC1HDAC2HDAC3 | |
| SCHEMBL27544136 | 0.80 | IDO1 (0.41) | IDO1HDAC8MAPTKDM4EHDAC1 | |
| SCHEMBL27552471 | 0.78 | HDAC3 (0.33) | IDO1HDAC8HTTHDAC1HDAC2 | |
| SCHEMBL27479163 | 0.78 | C5AR1 (0.47) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL6674459 | 0.78 | CACNA1C (0.43) | IDO1HDAC8HTR6 | |
| Hydrochloric Acid SCHEMBL27564406 | 0.77 | HDAC3 (0.32) | HDAC8HDAC1HDAC2HDAC3 | |
| Hydrochloric Acid SCHEMBL6675354 | 0.77 | CACNA1C (0.42) | IDO1HDAC8HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1172473-A | Aniline derivatives having nitric oxide synthase inhibitory activity | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1998-02-04 | — | — | CN | claimed |
| CN-1310169-A | Anils with nitric oxide synzyme inhibiting function | SHUGAI SEIYAKU K K (JP) | 2001-08-29 | — | — | CN | disclosed |
| CN-1172473-A | Aniline derivatives having nitric oxide synthase inhibitory activity | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1998-02-04 | — | — | CN | disclosed |