Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | GLS | O94925 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27564883 | 0.84 | CYP2C9 (0.45) | IDO1NAMPTHDAC1GLSSYK | |
| SCHEMBL27577235 | 0.81 | IDO1 (0.43) | IDO1NAMPTHDAC1GLSKDM4A | |
| SCHEMBL27564542 | 0.81 | JAK2 (0.39) | IDO1NAMPTHDAC1GLSKDM4A | |
| SCHEMBL27495178 | 0.80 | IDO1 (0.37) | IDO1HDAC1CA1MAPTKDM4E | |
| SCHEMBL27545134 | 0.79 | HDAC1 (0.44) | IDO1NAMPTHDAC1GLSKDM4A | |
| SCHEMBL27564508 | 0.78 | ALDH1A1 (0.44) | IDO1NAMPTGLSKDM4AMAPT | |
| SCHEMBL7740424 | 0.75 | MEN1 (0.36) | NAMPTGLSSYKMAPTMAPK1 | |
| SCHEMBL16486018 | 0.74 | AURKA (0.48) | NAMPTHDAC1GLSCA12CA1 | |
| SCHEMBL28745798 | 0.73 | HDAC1 (0.48) | IDO1NAMPTHDAC1GLS | |
| SCHEMBL17141855 | 0.73 | NAMPT (0.48) | NAMPTHDAC1CA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1310169-A | Anils with nitric oxide synzyme inhibiting function | SHUGAI SEIYAKU K K (JP) | 2001-08-29 | — | — | CN | disclosed |