Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.60 |
| ▸ | TDO2 | P48775 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4460308 | 0.90 | IDO1 (0.49) | IDO1TDO2TAAR1KMT2ANPC1 | |
| SCHEMBL27495004 | 0.82 | ACP3 (0.48) | TAAR1SIGMAR1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1147908 | 0.82 | ACP3 (0.48) | TAAR1SIGMAR1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL27495003 | 0.81 | MEN1 (0.48) | IDO1TDO2TAAR1KMT2ALMNA | |
| SCHEMBL31447616 | 0.76 | IDO1 (0.56) | IDO1TDO2TAAR1KMT2ANPC1 | |
| SCHEMBL23071686 | 0.76 | TAAR1 (0.65) | IDO1TDO2TAAR1KMT2ASIGMAR1 | |
| SCHEMBL21960138 | 0.74 | IDO1 (0.53) | IDO1TDO2KMT2ANPC1RAB9A | |
| SCHEMBL27479723 | 0.74 | SLC6A2 (0.53) | IDO1TAAR1KMT2AMEN1PNMT | |
| SCHEMBL12050856 | 0.73 | TAAR1 (0.74) | IDO1TAAR1PNMTAOC3HTR3E | |
| SCHEMBL5103603 | 0.73 | PNMT (0.58) | IDO1TDO2TAAR1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1219174-A | Inhibitors of protein farnesyl transferase | WARNER LAMBERT CO (US) | 1999-06-09 | — | — | CN | claimed |
| CN-1171874-C | Combinations of protein farnesyltransferase and HMG COA reductase inhibitors and their use to treat cancer | ��ʲ | 2004-10-20 | — | — | CN | disclosed |
| CN-1219174-A | Inhibitors of protein farnesyl transferase | WARNER LAMBERT CO (US) | 1999-06-09 | — | — | CN | disclosed |