SCHEMBL274968

SCHEMBL274968

O=C1CC(C(=O)OCc2ccccc2)C(=O)N1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 6/20 0.51
DDB1 Q16531 1/20 0.47
CRBN Q96SW2 1/20 0.47
BRD4 O60885 1/20 0.46
CREBBP Q92793 1/20 0.46
GLA P06280 1/20 0.45
TSHR P16473 1/20 0.45
GAA P10253 2/20 0.45
PKM P14618 1/20 0.45
FABP7 O15540 1/20 0.44
FABP5 Q01469 1/20 0.44
BACE1 P56817 1/20 0.44
NPC1 O15118 1/20 0.44
MAPK1 P28482 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5227458 1.00 GPBAR1 (0.51) GPBAR1DDB1CRBNBRD4CREBBP
SCHEMBL8777371 0.87 KMT2A (0.48) GPBAR1BRD4CREBBPNPC1RAB9A
SCHEMBL24818238 0.86 CRBN (0.53) GPBAR1DDB1CRBNTSHRGAA
SCHEMBL2245383 0.85 LMNA (0.55) GPBAR1GAASMN1; SMN2
SCHEMBL5552455 0.81 MMP1 (0.46) GPBAR1GLANPC1RAB9A
SCHEMBL24125403 0.79 ALDH1A1 (0.44) GPBAR1DDB1CRBNGLATSHR
SCHEMBL7369383 0.77 TSHR (0.49) GPBAR1DDB1CRBNBRD4CREBBP
SCHEMBL148443 0.77 GPBAR1 (0.46) GPBAR1DDB1CRBNBRD4CREBBP
SCHEMBL27280429 0.77 TSHR (0.49) GPBAR1DDB1CRBNBRD4CREBBP
SCHEMBL29088638 0.77 ALDH1A1 (0.46) DDB1CRBNTSHRRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 323 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119699315-A Storage method of biological tissue material 上海易桥医疗器械有限公司 2025-03-28 CN claimed
CN-119564933-A Preparation method of biological tissue material, prepared biological tissue material and application 上海易桥医疗器械有限公司 2025-03-07 CN claimed
CN-222131935-U Benzyloxy (BYO) carbonyl succinyl dehydration reaction device for imine production 四川安派博生物科技有限公司 2024-12-10 CN claimed
CN-118883784-A Melilotoin besylate method for detecting pregabalin 苏州正济药业有限公司 2024-11-01 CN claimed
CN-118749523-A Resistant sanitary pest control composition containing oxazine amide and application thereof 江苏功成生物科技有限公司 2024-10-11 CN claimed
CN-118624792-A Pretreatment method of organic matter sample and detection method of lysine substances 首都医科大学 2024-09-10 CN claimed
CN-118067886-A Method for measuring content of aging marker carboxymethyl lysine in skin 广州质量监督检测研究院 2024-05-24 CN claimed
CN-118063490-A Preparation method of ampicillin impurity 梯尔希(南京)药物研发有限公司 2024-05-24 CN claimed
CN-117658908-A Spiral charge folder molecule and preparation method and application thereof 吉林大学 2024-03-08 CN claimed
CN-116930478-A Thyroxine fluorescent conjugate and preparation method and application thereof 迈克生物股份有限公司 2023-10-24 CN claimed
CN-116183733-A Method for detecting amino acid and derivatives thereof 首都医科大学 2023-05-30 CN claimed
CN-114539106-B Synthetic method of stable isotope labeled taurinamide hydrochloride 梯尔希(南京)药物研发有限公司 2023-05-02 CN claimed
CN-114685391-A Preparation method of tetraazacyclododecane derivative 苏州美诺医药科技有限公司 2022-07-01 CN claimed
CN-114685390-A Preparation method of gadobutrol derivative 苏州美诺医药科技有限公司 2022-07-01 CN claimed
CN-114539106-A Synthetic method of stable isotope labeled tauryl amine hydrochloride 梯尔希(南京)药物研发有限公司 2022-05-27 CN claimed
CN-111056984-A Synthetic method of benzyloxycarbonyl succinimide 滨海吉尔多肽有限公司 2020-04-24 CN claimed
US-20260109714-A1 PYRIMIDINE-FUSED RING COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF GENFLEET THERAPEUTICS SHANGHAI INC (CN) 2026-04-23 US disclosed
EP-4707393-A1 DOUBLE-STRANDED SIRNA, CONJUGATE THEREOF AND USE THEREOF CMS Research & Development Pte. Ltd. (SG) 2026-03-11 EP disclosed
CN-1070409-A Prodrugs activated by targetted catalytic proteins IGEN INC (US) 1993-03-31 CN disclosed
WO-1993002703-A1 PRODRUGS ACTIVATED BY TARGETED CATALYTIC PROTEINS IGEN, INC. (US) 1993-02-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109714-A1 PYRIMIDINE-FUSED RING COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF KRAS, NRAS, HRAS GPBAR1 324/4885DDB1 459/4885CRBN 58/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.